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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
Anti-Exendin-4 ABS 012-20
品牌：
貨號：ABS 012-20
規格：200 μg
貨期：

Anti-Exendin-4
商品詳情 參考文獻 相關資料
Cat. No.
ABS 012-20
Product name
Anti-Exendin-4
Description

Mouse monoclonal antibody

Specificity

Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells

Immunogen

Synthetic exendin-4?

Application
ELISA
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/k

Gene ID
2740
Clone number
20
Epitope

The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39)amide.

Content

Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8oC without exposure to light. No precautions necessary during handling.
Target

Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster?Heloderma suspectum.?It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

Application 1

ELISA

ABS 012-20 binds to exendin-4 when coated on ELISA wells and reacts specifically with exendin-4 in solution giving a Ka of 1.6x10E8 in inhibition ELISA. The binding between ABS 012-20 and exendin-4 is disrupted by 4.5 M MgCl2.?
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