Anti-Procollagen type I C-terminal propeptide (human, PICP)
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Cat. No.
BTE 002-04
Product name
Anti-Procollagen type I C-terminal propeptide (human, PICP)
Description
Mouse monoclonal antibody
Specificity
BTE 002-04 is specific for for native PICP from amniotic fluid.
Immunogen
PICP purified from second trimester amniotic fluid by affinity chromatography
Application
ELISA
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass
IgG1/k
Gene ID
1277
Clone number
4
Epitope
Not determined
Content
Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8oC without exposure to light. No precautions necessary during handling.
Target
Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organic matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum is 100-300μg/ml.